汪剑波

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博士,教授,硕士生导师。2006年毕业于陕西科技大学获工学学士学位(导师:马建中教授);2012年毕业于中国科学技术大学化学系获理学博士学位(导师:宋钦华教授)。2012-2013年任职上海药明康德新药开发有限公司药物化学部。2013年加入嘉兴大学。2017-2018年在美国密歇根理工大学(导师:Liu Haiying)开展博士后(访问学者)研究,2018-2021年在复旦大学(导师:张凡教授)开展博士后研究。主要从事精细化工染料的合成和荧光性能研究,以及药物中间体工艺优化工作。主持及完成国家自然科学基金、浙江省自然科学基金项目及浙江省科技厅公益项目等科研项目。指导浙江师范大学、浙江工业大学及浙江理工大学等联培硕士生8名。以第一作者或通讯作者在Angew. Chem. Int. Ed., J. Hazard. Mater., Sensors & Actuators: B., Chem. Comm., Talanta, J. Mater. Chem. B等国际学术期刊上发表研究论文40,授权中国发明专利6项。

主持科研项目:

1.       浙江省自然科学基金探索项目(LY24B0600032024.01-2026.12,主持)

2.       浙江省自然科学基金探索项目(LY20B0600092020.01-2022.12,已结题,主持)

3.       中国博士后科学基金(2019M6513642019.04-2021.07,已结题,主持)

4.       国家自然科学基金青年项目(216061022017.01-2019.12,已结题,主持)

5.       浙江省科技厅公益项目(2016C370502016.01-2017.12,已结题,主持)

6.       浙江省自然科学基金青年项目(LQ15B0600052015.01-2017.12,已结题,主持)

7.       浙江省教育厅科研项目(Y201431756, 2014.10-2015.10, 已结题,主持)

发表学术论文(2019年至今):

1.         Mengyao Zhao, Weiping Lai, Benhao Li, Tianwen Bai, Chunyan Liu, Yanfei Lin, Shixuan An, Longhua Guo, Lei Li, Jianbo Wang*, Fan Zhang*. NIR-II Fluorescence Sensor Based on Steric Hindrance Regulated Molecular Packing for In Vivo Epilepsy Visualization. Angew. Chem. Int. Ed. 2024, e202403968. (自然指数期刊,SCI一区)

2.         Mengyao Zhao#, Jianbo Wang#,*, Zuhai Lei, Lingfei Lu, Shangfeng Wang, Hongxin Zhang, Benhao Li, Fan Zhang*. NIR-II pH Sensor with a FRET Adjustable Transition Point for In Situ Dynamic Tumor Microenvironment Visualization. Angew. Chem. Int. Ed. 2021, 60, 5091–5095. (自然指数期刊,SCI一区)

3.         Haiyi Niu, Tianqing Ye*, Liangyi Yao, Yanfei Lin, Kan Chen, Yanbo Zeng, Lei Li, Longhua Guo, Jianbo Wang*. A novel red-to-near-infrared AIE fluorescence probe for detection of Hg2+ with large stokes shift in plant and living cells. J. Hazard. Mater. 2024, 475, 134914. (SCI一区)

4.         Yaxin Sun, Yanyun Mao, Tianwen Bai, Tianqing Ye, Yanfei Lin, Fang Wang, Lei Li, Longhua Guo*, Haiying Liu* and Jianbo Wang*. An activated near-infrared mitochondrion-targetable fluorescent probe for rapid detection of NADH. Chem. Comm. 2024, 60, 5932–5935. (自然指数期刊,SCI二区)

5.         Min Zhou, Yanfei Lin, Tianwen Bai*, Tianqing Ye, Yanbo Zeng, Lei Li, Zhaosheng Qian, Longhua Guo*, Haiying Liu* and Jianbo Wang*. An activated near-infrared fluorescent probe with large Stokes shift for discrimination of bio-thiols. Sensors & Actuators: B, 2024, 414, 135994. (SCI一区)

6.         Qiangmin Yu, Yanyun Mao, Tianwen Bai*, Tianqing Ye, Zhengyuan Peng, Kan Chen, Longhua Guo, Lei Li* and Jianbo Wang*. Near-infrared Rhodols-based fluorescent probe with large Stokes shift for tracking of H2S in food spoilage and living cells. Spectrochim. Acta A, 2024, 315, 124250. (SCI二区)

7.         Shixuan An, Yanfei Lin*, Tianqing Ye, Tianwen Bai, Danyi He, Longhua Guo, Zhaosheng Qian, Lei Li, Haiying Liu* and Jianbo Wang*. An extra-large Stokes shift near-infrared fluorescent probe for specific detection and imaging of cysteine. Talanta, 2024, 267, 125247. (SCI一区)

8.         Yanyun Mao, Qiangmin Yu, Tianqing Ye, Man Xi*, Weiping Lai, Zhixiang Chen, Kan Chen*, Lei Li, Haiying Liu and Jianbo Wang*. New Rhodamine-based sensor for high-sensitivity fluorescence tracking of Cys and simultaneously colorimetric detection of H2S. Spectrochim. Acta A, 2024, 306, 123589. (SCI二区)

9.         Shixuan An, Yanfei Lin, Jianbo Wang*, Tianqing Ye, Yanyun Mao, Jian Zhang, Longhua Guo, Lei Lib, Zhaosheng Qian* and Haiying Liu*. Near-infrared mitochondria-targeted fluorescent probe with large Stokes shift for rapid and sensitive detection of cysteine/homocysteine and its bioimaging application. Sensors & Actuators: B, 2023, 374, 132799. (SCI一区)

10.     Weiping Lai, Yanfei Lin*, Tianqing Ye, Yating Yu, Hongwei Zhou, Lei Li, Guoliang Mao* and Jianbo Wang*. A novel near-infrared ratiometric fluorescence probe for Hg2+ based on quinoline-fused rhodamine dye. J Fluoresc, 2023, 33, 1413–1419. (SCI四区)

11.     Jiancheng Wu, Yanfei Lin*, Yating Yu, Yanbo Li, Tianqing Ye, Hongwei Zhou*, Lei Li, Jianbo Wang*. A highly selective and sensitive fluorescence probe based on Rhodol for imaging of endogenous peroxynitrite in living cells. Dyes Pigm, 2022, 206, 110597. (SCI二区)

12.     Lu Wang, Jianbo Wang*, Shuai Xia, Xinxin Wang, Yating Yu, Hongwei Zhou*, Haiying Liu*. A FRET-based near-infrared ratiometric fluorescent probe for detection of mitochondria biothiol. Talanta, 2020, 219, 121296. (SCI二区)

13.     Yating Yu, Jianbo Wang*, Huan Xiang, Linkun Ying, Chenyuan Wu, Hongwei Zhou*, Haiying Liu*. A new near-infrared ratiometric fluorescent probe based on quinoline-fused rhodamine dye for sensitive detection of cysteine and homocysteine in mitochondria. Dyes Pigm, 2020, 183, 108710. (SCI二区)

14.     Shuai Xia, Jianbo Wang*, Yibin Zhang*, Nick Whisman, Jianheng Bi, Tessa E. Steenwinkel, Shulin Wan, Jerry Medford, Momoko Tajiri, Rudy L. Luck*, Thomas Werner* and Haiying Liu*. Ratiometric fluorescent probes based on through-bond energy transfer of cyanine donors to near-infrared hemicyanine acceptors for mitochondrial pH detection and monitoring of mitophagy. J. Mater. Chem. B, 2020, 8, 1603–1615. (back cover) (SCI二区)

15.     Qingqing Wu, Jianlu Zheng, Wencui Zhang, Jianbo Wang*, Wenlang Liang*, Florian J. Stadler A new quinoline-derived highly-sensitive fluorescent probe for the detection, of hydrazine with excellent large-emission-shift ratiometric response. Talanta, 2019, 195, 857-864. (SCI二区)

16.     Shuai Xia, Mingxi Fang, Jianbo Wang*, Jianheng Bi, Wafa Mazi, Yibin Zhang, Rudy L. Luck*, Haiying Liu*. Near-infrared fluorescent probes with BODIPY donors and rhodamine and merocyanine acceptors for ratiometric determination of lysosomal pH variance. Sensors & Actuators: B, 2019, 294, 1-13. (SCI一区)

17.     Jianbo Wang*, Shuai Xia, Jianheng Bi, Yibin Zhang, Mingxi Fang, Rudy L. Luck*, Yanbo Zeng, Tzu-Ho Chen, Hsien-Ming Lee* and Haiying Liu*. Near-infrared fluorescent probes based on TBET and FRET rhodamine acceptors with different pKa values for sensitive ratiometric visualization of pH changes in live cells. J. Mater. Chem. B 2019, 7, 198–209. (back cover) (SCI二区)

 

授权专利:

1.  一种水溶性香豆素类荧光探针及其制备方法和应用 ZL201611029585.5 2018.10

2.  一种喹啉基近红外罗丹明荧光染料、比率荧光探针及其合成和应用 ZL202010717074.2 2021.10

3.  一种基于荧光共振能量转移检测生物硫醇的近红外比率荧光探针及其制备和应用 ZL202010566667.32022.04

4.  一种氟硼二吡咯类荧光探针、其制备方法及在金离子检测中的应用 ZL202110164306.62022.07

5.  一种用于快速灵敏检测过氧硝酸盐的Rhodol荧光探针及其制备方法和应用;ZL202210844439.7;2023.10

6.  近红外第二窗口检测pH的双通道比率荧光传感器及其制备方法和应用;ZL202210040382.52023.9

 

获奖情况:

1.  2019年嘉兴市自然科学学术奖三等奖

2.  2019年国际至尊97娱乐勤慎青年学者

3.  2016年嘉兴市自然科学学术奖二等奖

4.  指导本科生获得国创项目2项(20192022),浙江省新苗项目1项(2016);指导本科生获得省级竞赛一等奖2项,省级三等奖1项。

 

联系方式:

Email: wjb4207@mail.ustc.edu.cn; wangjianbo@fudan.edu.cn.

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